ニシムラ　ナオキ   NISHIMURA, Naoki   西村　直記 スポーツ科学部 スポーツ科学科 教授
言語種別	英語
発行・発表の年月	2021/06
形態種別	学術雑誌
査読	査読あり
標題	Gravity induced lower leg swelling can be ameliorated by ingestion of α-glucosyl hesperidin beverage
執筆形態	共同
掲載誌名	Fronties in Physiology, Environmental, Aviation and Space physiology
掲載区分	国外
担当範囲	First author
担当区分	筆頭著者
著者・共著者	Naoki Nishimura, Satoshi Iwase, Hiroko Takumi and Keiko Yamamoto
概要	We aimed to clarify the influence of intake of 4G-α-glucopyranosyl hesperidin (G-Hsp) beverage on the lower leg swelling caused by six hours of sitting in six healthy women. Increase in ankle % circumference was significantly less after the G-Hsp ingestion than after placebo. A significant difference was found between % circumference after the G-Hsp and the placebo, i.e., the calf swelling after placebo was significantly larger. A gradual increase in skin temperature at the lower limb was observed after G-Hsp ingestion while there was no change after placebo. Gravity induced calf and ankle swelling resulted by prolonged sitting can be ameliorated by oral ingestion of hesperidin-derived G-Hsp through production of nitric oxide. It might be helpful in preventing economy-class syndrome caused by enforced sitting for a long duration.